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Sunday heralds the initial Wear-Tyne derby since 2024, but which side will celebrate – Sunderland or the Magpies?
"Throughout the majority of last season, no one would have predicted the Wearside club getting promoted and being competitive with Eddie Howe's Newcastle, never mind being above them in the table," remarked analyst Chris Sutton.
"It is very different now, and the way Sunderland play convinces me they've got a genuine opportunity."
The analyst is providing forecasts for all 380 Premier League games this campaign, in competition with artificial intelligence, the public and a range of guests.
For week 16, he faces off against England Gaming star Daniel 'Stingray' Ray.
Ray is competing for honours for the England's esports team – the Football Association's official esports team – at the gaming title Uefa eEuro 2025 finals tournament, which will occur at Twickenham Stadium on Saturday.
Viewers can catch Uefa's video platform, IG Live and short-form video channels, as well as EA Sports FC Twitch and YouTube and England's Twitch.
Do you agree with their forecasts? You can make your own predictions below.
The most commonly selected scoreline selected for each game is featured in the tables at the end of this page.
Predicting the right outcome (selecting a win, draw or defeat) is worth 10 points. A perfect prediction earns 40 points.
Ray, who also plays his club side and the Premier League champions as well as England, is competing for the first time at the eEuros finals after passing the preliminary stage.
A group of eight will fly the flag at the finals in a knockout format, vying for a six-figure prize fund and a coveted spot in the world finals play-offs, with the Danish representative Anders Vejrgang defending the title he won last year.
"My mindset is really good for it," Ray said. "There's a really good coach by my side and training has been going well.
"It's always an honour to play for your country. Of course when you are younger, you fantasise about doing it as an actual footballer, but when you pursue a career in this profession and there is an chance to represent England, donning the national jersey is something special.
"I overcame Vejrgang 9-4 in qualifying to get here. I've played against him recently just in practice, and in other tournaments before - but I'd always lost to him in a tournament before.
"I believe he is the top competitor in the world so getting a win over him in a tournament like this just delivers a massive injection of confidence."
Premier League Forecasts
Saturday, 13 December
Chelsea vs Everton
Stamford Bridge, 15:00 GMT
Chelsea were impressive against Arsenal at the end of November, when they secured a point after being reduced to 10 men, and I was thinking here we go, they could potentially be title contenders.
However, since that game, however, they were overpowered by Leeds, looked flat against Bournemouth and this week got beaten by Atalanta in the Champions League.
So manager Enzo Maresca really needs a win here to return to winning ways, but it is a tough ask because the Toffees are such a threatening team.
Their key midfielders are playing exceptionally and Everton have got a bit of form at the moment.
Based on recent performances you would probably back the visitors, while the most sensible prediction would likely be a draw, but I am not going to be sensible.
The Blues have failed to given me any real reason to back them recently, but I just have a gut instinct Chelsea will take this one because they are at home and they are due a win.
Sutton's prediction: 2-1
Stingray's prediction: With this being at the Bridge, I am going to back Chelsea. I think they will start off really well and go 2-0 up, then Everton will nick one back but then Chelsea score late. 3-1
AI's prediction: 2-0
Liverpool vs Brighton
Anfield, 15:00 GMT
I'm attending this game and it will be intriguing to see what we get from Liverpool.
It was great to see for Reds boss Arne Slot to get such a great win at Inter Milan on Tuesday following all the discussion with Mohamed Salah this week.
Slot should not have to put up with that distraction. I know Salah has been a great for the club but fundamentally Slot just wants to win games and there is no ulterior motive in his team selection.
Liverpool changed their shape against Inter and went with a midfield diamond and two up top.
Everyone is going to be talking about whether Salah is back for this game, but the only way he is going to be brought back into the fold is if he says sorry.
Slot's primary concern will be on winning this game, but it is a tough one.
You could argue it is the same for most teams but I find Brighton so mercurial. I always feel they have got a goal in them, but they are quite open too.
The Merseysiders need to get back to winning consistently, but I am not sure how much their exertions at the San Siro will have drained them.
I have whacked a couple of Brighton players in my Fantasy Premier League side, so they will likely do poorly - but I do fancy get something at Anfield.
Sutton's prediction: 2-2
Stingray's prediction: This is a game which is going to give Liverpool a bit more of their confidence back. Obviously they had a good win in midweek and they can build more momentum here. 2-1
AI's prediction: 3-1
Sunday, 14 December
Sunderland vs Newcastle
Stadium of Light, 14:00 GMT
Sunderland have had the week off while Newcastle had to exert themselves against Bayer Leverkusen on Wednesday, only to be pegged back late on.
Apart from their excellent performance against Everton a couple of weeks ago, Newcastle's away form hasn't been great, particularly straight after they've played in the Champions League.
It is anticipated that that pattern to continue on Sunday, and their lack of freshness is likely to be a key element in how this game goes because of their rivals' high press.
We saw how incessant Regis le Bris's side are. They bullied the Gunners, and it was a joy to watch.
Everyone talks about how Granit Xhaka has been phenomenal for the Black Cats, and he has been superb, but Noah Sadiki, who plays next to him, has also been one of the best acquisitions and warrants praise too.
I am expecting this being the best game|most exciting fixture